Beerus is the most prevalent, but more so as a character and less an antagonist.
The rest are all complete
cardboard cutouts. If forced to choose, however, it'd probably be Zamasu or Jiren. The former has the benefit of being such a wall he couldn't be defeated by the main cast and his actions resulted in an entire timeline needing to be erased, whereas the latter seems more popular right now due to the ToP's length and his fight against Ultra Instinct Goku. Overall, Zamasu should be the winning choice as he's the only one of the bunch to really be a villain, with it being unlikely Jiren will have further impact on the series than being the guy who made Goku use a temporary transformation, especially when he's already been equalled or surpassed by Broly and thus has even less relevance of being a stable rival.