Best chemistry between antagonist/protagonist?

[Fantastische Hure]

Outside of DragonBall, because there's a thread for that.

I don't know. Maybe Atem/Thief-King. I thought InuYasha and Hiten for some reason also had good chemistry. Can't really tell why, maybe because in some-ways they feel like counter-parts. Mayyyyyybe. Also InuYasha & Sesshomaru.

 

[Papasmurf]

SHC and a white guy.

 

[Boo Brand Milk]

What can I say? It's love.

 

[SSJ2]

I just looked through my list of everything I've read and really couldn't come up with an answer. I was going to say Guts and Griffith, but they didn't interact all that much after Griffith became the true antagonist.

 

[Fantastische Hure]

I’d say it still counts, since it all presumably build-up to their fight anyway.

Jounouchi/Bandit Keith?

 

[Kyo]

Light/L

 

[Papasmurf]

Light/L

 

[Kyo]

Light/L

Probably not the literal best btw but it stood out when I searched my head for examples
I don't think most anime/manga is great at coming up with a good protag/antag pair

 

[Papasmurf]

Probably not the literal best btw but it stood out when I searched my head for examples
I don't think most anime/manga is great at coming up with a good protag/antag pair

What about Shinji and Fagworu though

 

[Yoshi]

I just looked through my list of everything I've read and really couldn't come up with an answer. I was going to say Guts and Griffith, but they didn't interact all that much after Griffith became the true antagonist.

Indeed. They only interacted twice after the Golden Age. That reminds me of how often Naruto and Sasuke interacted after Part I, as well.