Nobuo Uematsu
Also I spent ages trying to find this topic, because I thought it was in the anime section.
He's a legend, but I think Tajiri is immediately out. Pokemon is huge and was unique in some ways (like using the link cable, the whole idea of catching monsters, although there's a little similarity to Megami Tensei/Persona), but it's not really the foundation for an entire genre like DB or Zelda/Mario/Donkey Kong were.
Toriyama also did art for games, even if his art definitely doesn't have a lot of variety (so many characters look like a DB reject). Miyamoto worked on top-quality games for vastly different consoles (2D consoles to 3D), but I don't know how heavily involved he was in the process of making the games. With Toriyama it's more simple - he just had to come up with and draw a story, whereas with making games there are so many different parts to it that I can't easily know what Miyamoto actually did. Having said that, games being way more complex than manga I think makes being heavily involved in their development and design more impressive. Novels have existed for millennia, and while Toriyama wrote a good story and also was better than maybe anyone at drawing action sequences, he took a lot of inspiration from other stories and wasn't having to basically invent a new art form, like a pioneering game designer does. But maybe a game expert would come and say Miyamoto's games weren't wading into unchartered territory as much as I'm thinking. But I'm going for Miyamoto. Rename the forum to MarioZelda forum.